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您请求的操作仅限于组中的用户:定义/描述==脊柱裂Brea CM, Munakomi S.脊柱裂。InStatPearls [Internet] 2022年2月9日。StatPearls出版。一般来说，被定义为“神经管缺陷(' NTD')，由于下神经孔未关闭而导致，尽管也有人建议在某些情况下关闭的神经管可能重新打开。[参考文献]李建平，李建平。[https://journals.sagepub.com/doi/abs/10.1177/088307389000500413继发性神经管重开造成的神经管缺损模式。]儿童神经病学杂志。1990年10月,5(4):336 - 40。发育中的椎骨不能闭合不完整的神经管，导致神经管远端骨缺损。Copp AJ, Adzick NS, Chitty LS, Fletcher JM, Holmbeck GN, Shaw GM.脊柱裂。疾病引物。2015年4月30日;1(1):1-8。脊柱裂的确切病因尚不清楚，但可能与“遗传”、“环境”和“饮食因素”有关，这些因素可使某些个体易患脊柱裂。 The most commonly researched factor is the association of low levels of maternal '''folic acid'''. Folic acid is a vitamin present in many foods and is often added to breakfast cereals. It can also be found as a supplement in the pharmacy. It is thought to be involved in the development and formation of fetal cells and tissues, therefore, it is advised that folic acid should be taken daily in the upcoming months before conceiving and also during pregnancy Ray JG, Meier C, Vermeulen MJ, Boss S, Wyatt PR, Cole DE. [https://www.sciencedirect.com/science/article/pii/S0140673602119945 Association of neural tube defects and folic acid food fortification in Canada]. The Lancet. 2002 Dec 21;360(9350):2047-8..
{{#ev:youtube|jlDZA2PNW2o}}YouTube.Osmosis Spina bifida (myelomeningocele, meningocele, occulta) - causes, symptoms, treatment. Available at: http://www.youtube.com/watch?v=jlDZA2PNW2o (accessed 31 July 2020).

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