非霍奇金淋巴瘤的视图来源

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您请求的操作仅限于组中的用户:病因学==[[文件:淋巴瘤。png|右|无框|400x400px]]非霍奇金淋巴瘤(NHL)可能与多种因素有关,包括感染、环境因素、免疫缺陷状态、慢性炎症等。*不同类型的非霍奇金淋巴瘤有不同的病毒。*爱泼斯坦-巴尔病毒是一种DNA病毒,与某些类型的非霍奇金淋巴瘤的病因有关,包括伯基特淋巴瘤的一种地方性变异。*人类t细胞白血病病毒1型(HTLV-1)引起成人t细胞淋巴瘤。它诱导慢性抗原刺激和细胞因子失调,导致不受控制的B细胞或t细胞刺激和增殖。*丙型肝炎病毒(HCV)导致克隆b细胞扩增。脾边缘区淋巴瘤和弥漫性大B细胞淋巴瘤是由丙型肝炎病毒引起的NHL的一些亚型。*幽门螺杆菌感染与胃粘膜相关淋巴组织(MALT)淋巴瘤(一种原发性胃肠道淋巴瘤)的风险增加相关。*苯妥英、地高辛、TNF拮抗剂等药物也与非霍奇金淋巴瘤有关。此外,有机化学品、杀虫剂、苯氧类除草剂、木材防腐剂、灰尘、染发剂、溶剂、化疗和辐射暴露也与NHL的发展有关。 * Congenital immunodeficiency states associated with increased risk of NHL are Wiskott-Aldrich syndrome, severe combined immunodeficiency disease (SCID), and induced immunodeficiency states like immunosuppressant medications. Patients with AIDS (Acquired immunodeficiency syndrome) can have primary CNS lymphoma. * The autoimmune disorders like sjögren syndrome, rheumatoid arthritis, and Hashimoto thyroiditis are associated with an increased risk of NHL. Hashimoto's thyroiditis is associate with primary thyroid lymphomas. Celiac disease is also associated with an increased risk of non-Hodgkin lymphoma.

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