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您请求的操作仅限于组中的用户:====免疫和非免疫细胞==== *皮肤驻留免疫细胞通过主动采集环境抗原来促进组织稳态功能和保护身体。一些常驻免疫细胞迁移到淋巴结,要么诱导外周对组织自身抗原的耐受,要么启动强大的免疫反应。In infections or tissue injury, immune cells resident in the skin and those infiltrating from the periphery interact to create an intricate defense network to resolve the insult and restore the tissue to its original state. * Skin-resident myeloid cells include Langerhans cells, dermal dendritic cells, macrophages, mast cells, and eosinophils that contribute to skin homeostasis by secreting growth factors needed for the survival of keratinocytes, fibroblasts, and endothelial cells. They phagocytose debris and apoptotic cells and support vasculature integrity. In inflammatory conditions, myeloid cells respond immediately and produce pro-inflammatory mediators that drive cell activation and infiltrate the affected area by peripheral immune cells. Skin myeloid cells also serve as a link between the innate and adaptive immune systems. 回到 检索自"//m.houseofhawgs.com/Skin"
回到 检索自"//m.houseofhawgs.com/Skin"