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您请求的操作仅限于组中的用户:肌少症的临床评估肌少症研究的一个广泛领域是确定肌肉质量和功能下降在临床上具有重要意义的阈值。肌少症的几种临床定义已经提出。值得注意的定义包括欧洲老年人肌肉减少症工作组(EWGSOP)Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, bruy re O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM。[https://doi.org/10.1093/ageing/afy169肌肉减少症:修订的欧洲定义和诊断共识]。年龄与老龄化。2019年1月1日;48(1):16-31。,肌少症国际工作组(IWGS)Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, van Kan GA, Andrieu S, Bauer J, Breuille D, Cederholm T. https://linkinghub.elsevier.com/retrieve/pii/S1525861011000193肌少症:老年人未确诊的疾病。目前的共识定义:患病率、病因和后果。肌少症国际工作组]。美国医学主任协会杂志。2011年5月1日;12(4):249-56。, NIH骨骼肌减少症项目基金会Dam TT, Peters KW, Fragala M, Cawthon PM, Harris TB, McLean R, Shardell M, Alley DE, Kenny A, Ferrucci L, Guralnik J. [https://doi.org/10.1093/gerona/glu013骨骼肌减少症的循证操作标准比较]。 Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences. 2014 May 1;69(5):584-90., and the Society of Sarcopenia, Cachexia and Wasting DisordersMorley JE, Abbatecola AM, Argiles JM, Baracos V, Bauer J, Bhasin S, Cederholm T, Coats AJ, Cummings SR, Evans WJ, Fearon K. [https://doi.org/10.1016/j.jamda.2011.04.014 Sarcopenia with limited mobility: an international consensus]. Journal of the American Medical Directors Association. 2011 Jul 1;12(6):403-9.. The diagnostic criteria for some of these definitions is provided in Table 1 below. Most of the clinical definitions of sarcopenia include assessing appendicular lean muscle mass using a [[Dual Energy X-ray Absorptiometry (DEXA Scan)|DEXA]] scan, making it challenging to do a rapid assessment in clinical practice. Hence, [[SARC-F: A Simple Questionnaire to Rapidly Diagnose Sarcopenia|SARC-F]], a rapid assessment tool to identify an individual with sarcopenia, has been proposed. Nevertheless, screening of probable sarcopenia by [[SARC-F: A Simple Questionnaire to Rapidly Diagnose Sarcopenia|SARC-F]] should be followed by a formal diagnosis using DEXA-assessed appendicular lean mass and assessment of muscle function. Men generally have a higher muscle mass compared to women; hence, different cut points have been proposed to identify men and women with sarcopenia. {| class="wikitable" |+ ! colspan="4" |Table 1: Diagnostic criteria for sarcopenia |- !Diagnostic criteria !Definition of low muscle mass !Definition of low muscle strength !Criteria for poor muscle performance |- |European Working Group on Sarcopenia in Older People (EWGSOP) |ALM/height2 Men: ≤7.23 kg/m2 Women: ≤5.67 kg/m2 |Handgrip strength Men: <30 kg; Women: <20 kg |Gait speed: <0.8 m/s |- |International Working Group on Sarcopenia (IWGS) |ALM/height2 Men: ≤7.23 kg/m2 Women: ≤5.67 kg/m2 | - |Gait speed: <1.0 m/s |- |Foundation of NIH Sarcopenia Project |ALM/BMI Men: <0.789 Women: <0.512 |Handgrip strength Men: <26 kg; Women: <16 kg |Gait speed: <0.8 m/s |- | colspan="4" |ALM: Appendicular lean muscle mass (i.e., the sum of lean mass in both upper and lower limbs) BMI: Body mass index |}

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